BIOEFFECT EGF Eye Serum in Beauty: NA. BIOEFFECT EGF Eye Serum in Beauty: NA. BIOEFFECT offers a more concentrated approach to tackling puffy eyes and fine lines with the EGF Eye Serum. Formulated with a high EGF concentration, this gel-like eye serum absorbs quickly as you roll the steel applicator around the eyes to moisturize, firm, brighten, and minimize puffiness and fine lines.. EGF (Epidermal Growth Factor) is a protein in human skin that signals cells to boost collagen and elastin production to maintain healthy, firm, and youthful skin. Hyaluronic Acid hydrates and retains moisture in the skin. Free of fragrance, alcohol, oil, and parabens. 0.2 fl oz. Use day or night by gently pressing the base to release product, then rolling the cooling ball onto clean skin above and below the eye, and gently massaging with fingertips. Allow the serum to absorb completely for 3-5 minutes before applying makeup or sunscreen if used in the morning. BIOE-WU3. BES008. BIOEFFECT was founded by three scientists when they discovered, after ten years of research, a way to bioengineer a plant-based human replica of EGF (Epidermal Growth Factor) in barley. Their mission is to restore and maintain the skin's natural youthfulness and vitality through pure ingredients and truly effective advancements in skincare using biotechnology.